Sergey P. Klykov, for many years worked in the Institute of Applied Microbiology (Obolensk, Moscow Region). He is a co-author (with Victor V. Derbyshev who is the author of a non-structured model) of the integrated development model for the time-varying systems, and a co-author (with Vladimir V. Kurakov) of the development model in steady-state conditions. He performed calculations of experimental data on the integrated mathematical model of development.